Panc 08.13（人胰腺腺癌細(xì)胞）
CBP60684
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| I. General information | |
| Synonyms: | Panc 08.13 |
| Background: | Panc 08.13 is a pancreatic adenocarcinoma epithelial cell line derived in 1995 from a primary tumor removed from the head-of-the-pancreas of a male with pancreatic adenocarcinoma. |
| Species: | Homo sapiens, human |
| Tissue: | pancreas |
| Disease: | adenocarcinoma |
| Gender: | White, male, 85 years |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 20 hrs |
| DNA Profile: | Amelogenin: X CSF1PO: 11 D13S317: 13 D16S539: 13 D5S818: 13,14 D7S820: 11 THO1: 6,9.3 TPOX: 8,12 vWA: 18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+15%FBS+10ug/ml insulin Panc 08.13完全培養(yǎng)基，# CBP60684M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | MHC class I +; MHC class II - |
| Oncogene: | K-ras + Ref |
| Genes Expressed: | cytokeratins 7 and 18 |
| Cellular Products: | cytokeratins 7 and 18 |
| Tumor Formation: | Yes, forms tumors in nude or SCID mice |
| Comments: | The cell line exhibits a K-ras oncogene mutation at codon 12 where a GGT --> GAT mutation resulted in substitution of aspartic acid for glycine. The cells have a reported plating efficiency of 40%. For more information, please contact Cobioer (4008-750-250). |
